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Sytropin Review – Ingredients, Side Effects & Where to Buy

Expert opinion:

Not Recommended


Tired of swallowing handfuls of supplements every day? Well now, you can spray them. One of the most recent trends to take the sports nutrition industry by storm is spray supplements. Sytropin is a specially formulated spray supplement designed to promote an increase in human growth hormone (HGH).

Distributed by Speedwinds Nutrition, Sytropin spray has been formulated to boost endurance, increase lean muscle mass, enhance protein synthesis, reduce body fat, and increase energy levels.1

Marketed as a faster delivery of nutrients, the Sytropin HGH supplement offers an alternative to traditional methods of supplementation such as pills, powders or shakes.1

Sytropin reviews
Sytropin Supplement facts

Sytropin uses a proprietary blend which makes it difficult for customers to determine how likely these ingredients are able to increase HGH production.

Sytropin Ingredients

Ever wonder what makes some supplements effective and others fall flat? The ingredients and selected doses are two of the most important factors in finding a winning dietary supplement. While the Sytropin website highlights some of its powerful ingredients designed promote HGH production, for unknown reasons they do not include the exact doses used.

Below, we break down the latest science behind each ingredient and explain the possible benefits of adding them to your workout routine.

Alpha GPC – Alpha glycerylphosphorylcholine (GPC) is a choline compound marketed for its cognitive enhancing properties and potential to increase growth hormone.2 One preliminary study has noted a temporary increase in circulating growth hormone. Participants took one 600 mg dose of alpha GPC which enhanced power output by 14%.

Several studies have observed that supplementing with 100 – 200 mg of natural GABA can improve mood, reduce stress and anxiety.3

GABA Gamma-aminobutyric acid or GABA, is a neurotransmitter commonly found throughout the central nervous system. In the body, GABA acts as a depressant which helps regulate the nervous system during times of stress or neurological excitement.3 Low levels of GABA have been linked to anxiety, insomnia, depression, and epilepsy.

Glycine – A non-essential amino acid, glycine plays an important role in the central nervous system and may help promote energy production. Emerging scientific research shows promise for glycine supplementation improving sleep quality in individuals with mild sleep deprivation.4

L-Arginine – A conditionally essential amino acid, L-arginine is often taken by athletes to promote nitric oxide production and improve blood flow.9 For enhanced sports performance, standard doses range from 3-6 g.5

L-Dopa Bean Extract – A precursor to dopamine, levodopa or L-dopa is an amino acid that’s commonly used as a treatment for Parkinson’s disease. It’s been associated with increasing levels of dopamine and possibly growth hormone in the body.6,7

L-Glutamine – As one of the most abundant amino acids in the body, glutamine acts as a building block for proteins, supports the immune system and helps the body get rid of excess ammonia. Glutamine is stored in muscles and increased levels may be required during times of heavy exercise or injuries.8

Endurance athletes such as marathon runners often become sick after an event. Some researchers think this is due to depletion of glutamine and weakening of the immune system.8

L-Isoleucine – One of three branched chain amino acids (BCAA), isoleucine contributes to a diverse range of biological functions in the body including activating hormone secretion, regulating energy levels, wound healing, detoxification, supporting the immune system, and hemoglobin formation.9

L-Valine – The second branched chain amino acid, valine encourages tissue repair and muscle growth. In the body, valine also supports muscle coordination, stabilizing mood and maintaining cognitive functions.10

L-Lysine – L-Lysine is an essential amino acid that is crucial for proper growth, protein synthesis and collagen formation. Collagen is used throughout the body for connective tissues, and some studies have noted lysine may aid muscle recovery for athletes. Further, lysine acts as a precursor for l-carnitine, which is responsible for energy production.11

Moomiyo Extract – Traditionally used in Ayurveda medicine, moomiyo also known as shilajit, is a mixture of minerals claimed to have antioxidant, anti-inflammatory, anabolic and adaptogen (stress-fighting) properties.16 To date, limited studies have been conducted on its efficacy, but one study has noted a 23.5% increase in serum testosterone in infertile men when they supplemented 200 mg of moomiyo for 90 days.12,13

Ornithine Alpha Ketoglutarate – Ornithine alpha ketoglutarate (OKG) is a substance that’s involved in cellular growth and repair. OKG is theorized to activate muscle growth and secretion of anabolic hormones, thus generating interest from athletes.14

How to Use Sytropin

According to the Sytropin directions, users should take two full sprays each morning. For optimal absorption, users should spray under the tongue and let absorb for two minutes after each spray. For maximum results, take an additional four sprays before going to bed for a daily total of six sprays.

Sytropin does not need to be swallowed as it is intended to be absorbed through the lining of the mouth.

Sytropin Side Effects

According to the Sytropin website, there are no currently known negative side effects of taking their product and it can be taken by adults of all health statuses. Without a list of possible side effects, it may leave customers wondering is Sytropin safe?

Based upon the ingredients used and the most up to date scientific research, BHO has compiled possible side effects that may occur from taking Sytropin.

In some users, arginine may cause lower blood pressure, as a result of increased vasodilation. Synthetic GABA supplements may have side effects including dizziness or drowsiness. However, supplementing with natural GABA has been observed to be well tolerated and almost free of side effects. As a part of a proprietary blend, it’s unknown which form of GABA is used in Sytropin spray.

Glycine is generally regarded as safe, with doses up to 45 g being used without reported side effects. Additionally, valine, glutamine, isoleucine, and leucine are generally well-tolerated and carry very little side effects until dosed around 30 g. Currently, OKG has no known interactions with supplements, food, or other compounds. There are also no well-known side effects for OKG. It should be noted, the sale of Moomiyo has been banned in countries such as Canada due to high levels of heavy metals detected in tested Ayurveda products.

Does Sytropin Work?

In a recent pilot study, 3 g of glycine was shown to improve sleep quality in individuals, with participants self-reporting they felt more rested the following morning.4 Combined with GABA, which can reduce anxiety and stress, users may feel more calm and less stressed. A lack of lysine in the body can cause fatigue, slow growth, irritability, and loss of appetite – factors which can all negatively affect sports performance.11 With several BCAAs and amino acids, users who are already deficient in these areas may feel a minor increase in energy and possibly benefit from enhanced muscle tissue repair and protein synthesis. Preliminary evidence supports OKG’s ability to enhance cell repair in elderly and hospital-bound subjects. However, there is currently no scientific evidence to support any benefits for healthy athletes.14

Although Sytropin spray includes a blend of amino acids, herbs and BCAA’s that may provide minor support for athletic performance, there is little evidence to support these ingredients increasing HGH production. Further, there is an extremely limited amount of scientific studies that have evaluated the efficacy of spray supplements. While they do provide an alternative method of delivery which reduces gastrointestinal side effects, the rate of absorption and full range of benefits remain unclear and require more scientific research.

Sytropin Reviews

While Sytropin’s website offers several customer testimonials, during our research we found that something customers love most about this product is the unique formula. Sytropin is one of the only products on the market that offer their ingredients as part of an oral spray. This makes the product a great alternative for anyone who does not like taking pills, or having to mix together messy workout powders.1

Where to Buy Sytropin

Sytropin HGH spray can be purchased exclusively online through the Sytropin website. For the price of shipping and handling, users receive a full 30-day supply of the product, and can try it before deciding if they would like to continue using it.

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Scientific Research Referenced in this Article

  1. (n.d.). Sytropin. Retrieved January 26, 2017 from – View Reference
  2. Ziegenfuss, T., Landis, J., & Hofheins, J. (2008). Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Journal of the International Society of Sports Nutrition, 5(Suppl 1), P15. doi:1186/1550-2783-5-s1-p15
  3. Thorne Research Inc. (2007). Gamma- aminobutyric acid (GABA). Alternative Medicine Review, 12(3), 274-279. Retrieved January 26, 2017 from http://altmedrev.com/publications/12/3/274.pdf
  4. INAGAWA, K., HIRAOKA, T., KOHDA, T., YAMADERA, W., & TAKAHASHI, M. (2006). Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep and Biological Rhythms4(1), 75-77. doi:1111/j.1479-8425.2006.00193.x
  5. S. National Library of Medicine. (2016, May 3). L-arginine. Retrieved July 26, 2017 from https://medlineplus.gov/druginfo/natural/875.html
  6. L-dopa. (n.d.) Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. (2003). Retrieved January 26 2017 from http://medical-dictionary.thefreedictionary.com/l-dopa
  7. KANSAL, P. C., BUSE, J., TALBERT, O. R., & BUSE, M. G. (1972). The Effect ofl-Dopa on Plasma Growth Hormone, Insulin, and Thyroxine. The Journal of Clinical Endocrinology & Metabolism34(1), 99-105. doi:1210/jcem-34-1-99
  8. University of Maryland Medical Center. (2015, August 5). Glutamine. Retrieved January 26, 2017 from https://umm.edu/health/medical/altmed/supplement/glutamine
  9. National Center for Biotechnology Information. PubChem Compound Database; CID=6306. Retrieved January 26, 2017 from https://pubchem.ncbi.nlm.nih.gov/compound/6306
  10. National Center for Biotechnology Information. PubChem Compound Database; CID=6287. Retrieved January 26, 2017 from https://pubchem.ncbi.nlm.nih.gov/compound/6287
  11. University of Maryland Medical Center. (2015, June 22). Lysine. Retrieved January 26, 2017 from http://umm.edu/health/medical/altmed/supplement/lysine
  12. Stohs, S. (2014). Safety and Efficacy of Shilajit (Mumie, Moomiyo. Phytotherapy Research,28(4), 475-479. doi:1002/ptr.5018
  13. Biswas, T. K., Pandit, S., Mondal, S., Biswas, S. K., Jana, U., Ghosh, T., & Auddy, B. (2010). Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia, 42(1), 48-56. doi:1111/j.1439-0272.2009.00956.x
  14. University of Michigan: Michigan Medicine. (2015, March 8). Ornithine Alpha-Ketoglutarate for Sports & Fitness. Retrieved January 26, 2017 from http://www.uofmhealth.org/health-library/hn-3890004#hn-3890004-dosage-side-effects

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