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Plexus Slim Review: Weight Loss, Ingredients, Side Effects, Cost & More

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Not Recommended

Plexus Slim

In 2011, the wellness company Plexus Worldwide launched their first product, a weight loss aid called Plexus Slim. On their website, they claim that Plexus Slim is clinically proven to help people lose weight, in addition to improving gut health. Plexus Slim products are often sold in tandem with other Plexus products, as in the Plexus Slim and Accelerator combo (which includes a supplement designed to burn fat and increase metabolism).1

What is Plexus Slim? The so-called “pink drink” is sold in powder form, getting its signature pink color when dissolved in water. Its ingredient list includes only 3 entries: a proprietary formula called the Plexus Slim Blend, one mineral, and prebiotics.  The Plexus Slim ingredients list on the product website showcases three of these as “featured ingredients”, including chromium, green coffee bean extract, and prebiotics.1

In this unsponsored review, you’ll learn about the science behind the ingredients, how to use Plexus Slim, before and after weight loss results, how to find it, and side effects of Plexus Slim.

What is Plexus Slim

The powder comes in single serve packets that are to be mixed into water, creating its signature pink color.

Plexus Slim Ingredients Label

The Plexus Slim proprietary blend includes three fruit extracts, two of which are commonly used in many weight loss supplements: green coffee extract and garcinia cambogia extract.

Plexus Slim Ingredients

The Plexus Slim ingredients label includes three main parts—chromium, xylooligosaccharides, and the proprietary Plexus Slim Blend. Green coffee bean extract, garcinia cambogia fruit extract, and alpha lipoic acid all appear on the Plexus Slim ingredient list as part of the proprietary formula.1 However, neither the Plexus slim ingredients list or supplement facts label details how much of each is included in the blend.

Xylooligosaccharides (XOL): 1000mg – This is a prebiotic, a non-digestible fiber that nourishes the good bacteria already present in the gut. There is an increasing amount of evidence showing that the gut microbiota is a factor in both the development and prevention of various diseases. One comprehensive study on XOL’s effect on the body did not record any changes in body weight. However, the researchers noted that the changes in certain bacteria (a decrease in Firmicutes and increase in Oscillospira) suggest a potential role of XOL in weight management.6

A prebiotic is a non-digestible food item that helps to nourish the good bacteria already in your gut. A probiotic is a microorganism thought to have health benefits when consumed.6, 10

Chromium: 200 mcg – A mineral and essential nutrient required for the chemical breakdown of carbohydrates, proteins, and fats, chromium is often included in weight loss supplements. It increases insulin activity, which in turn lowers blood glucose levels; it is also believed to act as an appetite suppressant. One study found that participants who took doses of chromium lost 1 kilogram more body weight during the study than the placebo group.5

Plexus Slim Blend: 531 mg

Green coffee bean extract (GCE) – This extract found in raw or green coffee is thought to be a slimming agent and is marketed as a weight loss aid. One systematic review examining three human GCE trials concluded that intake of GCE can promote weight loss. The mechanisms responsible are thought to be the thermogenic effect of caffeine as well as the effects of other pharmacologically active substances present in coffee, such as chlorogenic acid.3

Garcinia cambogia fruit extract – This extract is derived from a fruit native to South Asia. The compound hydroxycitric acid (HCA) is the active ingredient extracted from the fruit, and used in many weight loss supplements. Some research suggests that HCA works by inhibiting certain enzyme activity; other studies report that HCA increases serotonin levels, resulting in appetite suppression. A systematic review that analyzed 12 HCA trials concluded that HCA may generate weight loss on the short-term, but that additional studies are required to determine its long-term effects.4

Alpha lipoic acid – This acid is essential for aerobic metabolism and has been linked to weight loss. In a human trial involving 360 obese individuals, those taking 1800mg of alpha lipoic acid experienced significantly more weight loss than the placebo group. Researchers in this trial found no serious side effects and concluded that alpha lipoic acid may be considered an adjunctive therapy for obesity.7

Mulberry fruit extract – In traditional Chinese medicine, mulberry fruit was used to protect the liver and lower blood pressure. More recently, one study showed that when combined with mulberry leaf extract, it effectively helped improve obesity, inflammation and oxidative stress in rats, showing promise as a way to treat and possibly prevent obesity.8, 9

How to Take Plexus Slim

The Plexus Slim instructions on the product website instruct users to mix one packet of the product with 12-20 ounces of cold water.

Did you know: It is not recommended to mix Plexus Slim with hot water as it could negatively influence the stability of the green coffee extract, which would make the product less effective.1

To lose weight, Plexus explains that the best way to take Plexus Slim is by consuming a Plexus Slim drink 30 minutes before a meal. To support your gut microbiome, they instruct users to have a Slim drink at any time during the day.1

What Does Plexus Slim Taste Like?

The Plexus Slim pink drink comes in three flavors—raspberry, lemon, and watermelon. One Plexus Slim review on the website describes the watermelon flavor as tasting like Jolly Rancher watermelon candy.1

Plexus Slim Side Effects & Dangers

Is Plexus Slim safe? On their website, Plexus states that the supplement is safe and that the only side effect may be initial bloating or gas resulting from ingestion of prebiotics.1

Anecdotal evidence from Plexus Slim reviews express concern over the risk of fainting from low blood pressure, which could result from losing too much weight too quickly. Other Plexus reviews mention side effects such as nausea, restlessness, and heartburn. For some, these Plexus Slim dangers may pose a risk; others have used the product without complications.

In addition, while there aren’t any long-term studies on the effects of Plexus Slim, liver damage has been brought up by those who are concerned that the Slim formula supplies an overdose of several vitamins and minerals, but there is no evidence that supports this theory.

Plexus Slim While Pregnant

The Plexus Slim official product page recommends that you check with your doctor before taking Plexus Slim while pregnant. The label also advises users to check with a doctor before using Plexus Slim and breastfeeding.2

Does Plexus Work?

We’ve informed you on several of the ingredients in the formula, but does Plexus Slim work?

An in vitro, or test tube, test made to mimic the human gastrointestinal system found that Plexus Slim increased the levels of 3 different gut bacteria by over 200 times.

The official website lists various Plexus Slim success stories, including results from a clinical trial in which users lost 5.4 pounds in 8 weeks while taking the supplement twice a day. This study examined both Plexus weight loss results and other supposed benefits of Plexus Slim, such as increased counts of Lactobacillus bacteria, Bifidobacterium bacteria, and Akkermansia microbes.1

How Long Does Plexus Slim Take to Work?

If using Plexus for weight loss, the product website states you can lose up to 5.4 pounds within 60 days, according to their clinical studies. They also claim that you’ll feel better and notice an improvement in your mood within 30 days.1

Does Plexus Slim Work Without the Accelerator?

In their clinical trial, Plexus Slim weight loss mentioned above were measured independently of the Accelerator supplement. While the Accelerator could possibly help speed up weight loss, there is nothing to indicate that Plexus Slim will not work without it.

Plexus Slim Reviews

Based on the research behind the ingredients, its clinical trial, and various Plexus Slim testimonials, it is likely that this pink drink will help balance your gut health and promote weight loss when combined with a healthy lifestyle. Some customers have reported that they experienced amazing weight loss results from adding Plexus Slim to their routine, even sharing impressive before and after photos.

Plexus Slim Cost

The Plexus Slim price listed on the official website is $87.95. The package includes 30 single-serving packets, which means that the cost of Plexus Slim per serving is approximately $3.00.

Because people use the product differently, the in-depth answer to “how much is Plexus Slim?” will differ per user. As a rule of thumb, the recommended regimen of two servings per day results in a per diem cost of $6.00.

Where to Buy Plexus Slim

There are several ways to order Plexus Slim, with most options conveniently online. You can purchase directly from the official website, or you can also go through third party online retailers to buy Plexus Slim; Amazon and Ebay are two examples.

If you don’t like to buy online, you can buy Plexus Slim in person. Check to see if there’s a Plexus Slim ambassador in your area—these Plexus ambassadors work as independent representatives for the company and earn a commission on the products they sell.

Can You Buy Plexus Slim in Stores?

Plexus Slim is not sold in stores. You can only buy it online or through a local rep (called an Ambassador).

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Scientific Research Referenced in this Article

  1. (2017) Plexus Worldwide. Retrieved from – View Reference
  2. Plexus Worldwide Shop. Retrieved from: – View Reference
  3. Onakpoya, I., Terry, R., & Ernst, E. (2011). The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Gastroenterology Research and Practice, 2011, 382852. Retrieved from http://doi.org/10.1155/2011/382852
  4. Onakpoya, I., Hung, S. K., Perry, R., Wider, B., & Ernst, E. (2011). The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Journal of Obesity, 2011, 509038. Retrieved from http://doi.org/10.1155/2011/509038
  5. Tian H., Guo X., Wang X., He Z., Sun R., Ge S., Zhang Z. (2013). Chromium picolinate supplementation for overweight or obese adults. Cochrane Database of Systematic Reviews. 11:CD010063. DOI: 10.1002/14651858
  6. Yang, J., Summanen, P. H., Henning, S. M., Hsu, M., Lam, H., Huang, J., … Li, Z. (2015). Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study. Frontiers in Physiology, 6, 216. Retrieved from http://doi.org/10.3389/fphys.2015.00216
  7. Koh, Eun Hee et al. Effects of Alpha-Lipoic Acid on Body Weight in Obese Subjects. (2011) The American Journal of Medicine, 124(1), 85.e1 – 85.e8. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/21187189
  8. Chen, C. C., Liu, L. K., Hsu, J. D., Huang, H. P., Yang, M. Y., & Wang, C. J. (2005). Mulberry extract inhibits the development of atherosclerosis in cholesterol-fed rabbits. Food chemistry91(4), 601-607. https://doi.org/10.1016/j.foodchem.2004.06.039
  9. Hyun Hwa Lim, Soo Jin Yang, Yuri Kim, Myoungsook Lee, and Yunsook Lim (2013). Journal of Medicinal Food, 16(8): 673-680. https://doi.org/10.1089/jmf.2012.2582
  10. Guarner, F. & Schaafsma, G.J. (1998). Probiotics. International Journal of Food Microbiology,39(3), 237-238. http://dx.doi.org/10.1016/S0168-1605(97)00136-0

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