347,182k Readers
Trusted by Consumers and Businesses

BioMuscle XR Reviews, Side Effects & Ingredients – Does It Work?

Expert opinion:

Not Recommended

What is BioMuscle XR?

Looking to increase muscle mass and size? BioMuscle XR is one of the latest workout supplements claiming to activate increased muscle growth and enhance athletic performance.

With scientifically-researched ingredients, this formula contains no fillers and is designed to improve athletic endurance, enhance performance and promote muscle growth. BioMuscle appears to be distributed by a company that goes by the same name, but we were unable to find an official company website.

BioMuscle XR reviews
Bio Muscle ingredients

BioMuscle combines three unique forms or arginine, citrulline and dipotassium phosphate in a proprietary blend.

BioMuscle XR Ingredients

On the current Bio Muscle website, for unknown reasons there is no complete list of ingredients available. While the site discusses several key ingredients (nitric oxide, arginine and creatine) no dose is provided.

After some investigation, we have uncovered that BioMuscle XR combines five active ingredients in their proprietary blend. Below, we explain how these ingredients work in the body to possibly improve your sports performance and recovery.

L-Arginine Alpha Ketoglutarate 2-1 –L-arginine alpha-ketoglutarate combines arginine and alpha ketoglutarate, a salt derived from glutamine with glutamate sparing and ergogenic (performance-enhancing) properties. The two are combined with the goal of increasing nitric oxide (N.O.) production, which can influence muscle growth, improve blood flow, and promote muscle endurance.2

L-Arginine – L-arginine is a conditionally essential amino acid involved in protein metabolism, hormone secretion, creatine production and triggers nitric oxide production, which widens and relaxes blood vessels.3,4 In the body, arginine can help delay fatigue and active the immune system.4

L-Arginine Monohydrochloride – Arginine monohydrochloride is a salt of arginine and a precursor of nitric oxide. This form of arginine is believed to increase the absorption of the amino acid, and perhaps strengthen the effect.5

On the BioMuscle website, creatine is listed as one of the ingredients in their formula. However, when we obtained the product, there was no creatine listed in the supplement facts. It is unclear whether creatine was in a previous formula, or if the information listed on the website is outdated/incorrect.

L-Citrulline – Another amino acid, citrulline is also converted into arginine in the body. Used to increase endurance, reduce fatigue and improve ammonia recycling, citrulline can also benefit cardiovascular health. In recent studies, 6,000 mg of citrulline appears to be the minimum dose to improve sports performance and endurance.6,10

Dipotassium Phosphate – Dipotassium phosphate is a phosphate salt that is claimed to boost athletic performance by enhancing blood flow to muscles. Preliminary research indicates that taking phosphate salts four times daily improves sports performance modestly in male cyclists.7

How to use BioMuscle XR

According to the BioMuscle XR Growth Accelerator label, users should take two capsules, 1-2 times daily for optimal results.

BioMuscle XR Side Effects

The Bio Muscle website does not list any potential side effects users may experience. To keep our readers informed, we have compiled a list of potential side effects based upon the latest scientific research.

Supplementing with arginine has been reported to potentially cause gastrointestinal issues, including abdominal pain, diarrhea, and bloating.8,9 In higher doses, arginine has also been observed to affect blood sugar levels and lower blood pressure.9 Phosphate salts may irritate the digestive tract and cause diarrhea, constipation or upset stomach. When taken over time, phosphate salts may disrupt the natural balance of phosphate in the body.7

Does BioMuscle XR Work?

Based upon the most recent scientific research, and known dosages, we explain which of this product’s claims have evidence to support them.

In the body, arginine can trigger N.O. production, improve blood flow and increase insulin hormone levels. To enhance sports performance and body composition, scientific research has used doses ranging from 3-21 g. This range has been noted to enhance endurance and improve protein synthesis, which can lead to an increase in muscle size.8

When taking BioMuscle XR, users may notice a small increase in energy. In the body, BioMuscle may increase blood flow to a minor extent. After extended supplementation, arginine and citrulline may enhance the immune system in some users.6,8

BioMuscle XR Reviews

The customer testimonials for this product tend to be positive. Customers have reported that they were pleasantly surprised that they experienced no side effects from taking the product, and really liked the portable, easy to consume formula. A lot of users suggest that they experienced muscle gains shortly after they started taking the product.

Where to Buy BioMuscle XR

Wondering where you can buy Bio Testosterone XR? BioMucle XR is exclusively sold online and is not currently carried in major supplement retailers.

Before purchasing, potential buyers often rely on professional endorsements or certifications to vouch that the product is effective. BioMuscle XR does not advertise if they currently have any independent certifications or athlete endorsements. While these factors help build a product’s credibility, their absence does not necessarily make BioMuscle XR a scam or infective.

BioMuscle XR Price

For the price of shipping and handling, users receive a full 30-day supply of the product, and can try it before deciding if they would like to continue using it.

See our #1 Recommended Muscle Building Product


Scientific Research Referenced in this Article

  1. BioMuscle XR. (2017). BioMuscle XR. Retrieved January 12, 2017 from – View Reference
  2. Wax, B., Kavazis, A., Webb, H., & Brown, S. (2012). Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. Journal of the International Society of Sports Nutrition,9(1), 17.doi:1186/1550-2783-9-17
  3. Health Canada. (2010, May 25). Monograph: L-Arginine. Retrieved January 12, 2017 from http://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=124
  4. National Center for Biotechnology Information. PubChem Compound Database; CID=6322. Retrieved January 12, 2017 from https://pubchem.ncbi.nlm.nih.gov/compound/6322
  5. National Center for Biotechnology Information. PubChem Compound Database; CID=66250. Retrieved June 22, 2017 from https://pubchem.ncbi.nlm.nih.gov/compound/66250
  6. Bendahan, D., Mattei, J. P., Ghattas, B., Confort-Gouny, S., Le Guern, M. E., & Cozzone, P. J. (2002). Citrulline/malate promotes aerobic energy production in human exercising muscle. British Journal of Sports Medicine36(4), 282-289. doi:1136/bjsm.36.4.282
  7. U.S. National Library of Medicine: Medline Plus. (2016, February 9). Phosphate salts. Retrieved January 13, 2017 from https://medlineplus.gov/druginfo/natural/735.html
  8. U.S. National Library of Medicine: Medline Plus. (2016, May 3). L-arginine. Retrieved June 21, 2017 from https://medlineplus.gov/druginfo/natural/875.html
  9. Mayo Clinic. (2013, November 1). Arginine – Safety. Retrieved January 12, 2017 from http://www.mayoclinic.org/drugs-supplements/arginine/safety/HRB-20058733
  10. Pérez-Guisado, J., & Jakeman, P. M. (2010). Citrulline Malate Enhances Athletic Anaerobic Performance and Relieves Muscle Soreness. Journal of Strength and Conditioning Research, 24(5), 1215-1222. doi: 10.1519/jsc.0b013e3181cb28e0

See our #1 Recommended Muscle Building Product

Recommended product

Product Rating


Tap Here